Kidney Failure: Symptoms, Causes, and Stages

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Kidney Failure: Symptoms, Causes, and Stages

Your kidneys are the silent heroes of your body. They work nonstop, day and night, filtering your blood, balancing your fluids, removing toxins, and keeping you healthy.

When your kidneys begin to struggle, your entire body feels the impact. You will feel tired, experience swelling, and be in discomfort. 

The scariest part is that kidney failure symptoms are often quiet. Before you notice any major symptoms, it is too late. 

The damage may already be serious.

Therefore, listening to your body is very important. Even the smallest of the signs matters. The sooner you find these clues, the sooner you can protect your kidneys, your health, and your life.

We at NU hospitals, the leading hospital in India for Urology and Nephrology, are here to help you. Follow this blog to learn more about kidney failure, kidney failure symptoms, kidney failure stages, and causes. 

What Is Kidney Failure?

When kidney failure happens, your kidneys are unable to filter waste, balance your fluids, or manage electrolytes.

It is called end-stage renal disease, the final stage when your kidneys can no longer work and requires dialysis or a transplant. 

Kidney Failure Symptoms

The greatest challenge is catching this condition early.  The first signs are usually silent. People usually take these signs lightly as normal tiredness or stress. However, paying attention to these small changes is important.

What are the first signs of kidney failure?

The early warning signs are usually related to fluid balance and waste buildup.

Changes in Urination:

  • Need to urinate more often, especially at night.

  • Foamy or bubbly urine due to excess protein.

  • Blood in the urine.

Swelling (Edema):

  • Swollen feet, ankles, and legs.

  • Swelling around your eyes, particularly in the morning.

Fatigue and Weakness:

  • Feeling tired, even after rest.

  • Difficulty concentrating or brain fog.

  • This symptom is usually linked to the development of anemia.

Skin Issues:

  • Constant itchy or dry skin.

Metallic Taste and Nausea:

  • A constant bad taste in the mouth.

  • Loss of appetite and unexplained weight loss.

If you notice these kidney failure symptoms, don't wait. A simple blood test can help you get clarity.

Causes of kidney failure

There are several causes of kidney failure. Understanding these main triggers is important for the prevention of the disease.

  • Diabetes (Type 1 and Type 2)

High blood sugar levels over time damage the filtering units in your kidneys. This is the leading cause of kidney disease globally.

  • High Blood Pressure (Hypertension)

Uncontrolled high blood pressure narrows the blood vessels supplying your kidneys, starving them of oxygen and nutrients. It is the second leading cause of kidney failure.

  • Glomerulonephritis

Inflammation of your glomeruli, the filters inside the kidney. This can be caused due to infections, autoimmune diseases such as  Lupus, or certain medications.

  • Polycystic Kidney Disease (PKD)

It is a genetic condition where cysts grow on your kidneys, eventually crowding out the normal filtering tissue.

  • Obstructive Issues

Blockages caused by kidney stones, tumors, or an enlarged prostate can prevent urine from flowing out and cause pressure buildup.

Kidney Failure Stages

Kidney disease is divided into five stages, based on the Glomerular Filtration Rate (GFR). GFR is basically calculated with serum creatinine value for clinical purpose. GFR measures how well your kidneys are filtering blood. The lower the GFR, the worse the function.

Stage

Description of Kidney Damage

GFR (mL/min)

Management 

Stage 1

Mild kidney damage, but kidney function is normal 
90 or higher
Focus on risk reduction and diagnosis of the main cause of kidney disease.

Stage 2

Mild reduction in function
60–89
Focus on lifestyle changes and controlling blood pressure/sugar.

Stage 3A/3B

Moderate reduction in function. 
Symptoms usually start in this stage
30–59
Careful medication management. 
Dietary restrictions begin in this stage.

Stage 4

Severe reduction in function.
15–29
Preparing for treatment options such as dialysis or a kidney transplant. 

Stage 5

End-Stage Renal Disease (ESRD) or Kidney Failure
Below 15
Dialysis or kidney transplantation is required for survival.

 

Managing Kidney Failure: Treatment 

Facing Kidney Failure does not mean the end of your life. With the help of proper treatment, you can manage your condition better. 

Can I reverse kidney damage?

For chronic Kidney Failure, the damage that has already happened is, therefore, it is usually not reversible. However, you can stop or slow down further progression. Management of your blood pressure and blood sugar is the best way to preserve your remaining kidney function and delay the need for dialysis or transplant.

Step 1: Supportive Care

This starts immediately after diagnosis. It involves controlling the effects of kidney disease:

  • Diet

A low-sodium, low-potassium, and low-phosphorus diet is usually required. Protein intake may also be controlled.

  • Medication

Drugs to control blood pressure and other conditions. 

Step 2: Renal Replacement Therapy (RRT)

After reaching end-stage renal disease (Stage 5), other serious treatments are needed to help with the kidneys' filtering function.

Kidney failure dialysis: This is the most common RRT (Renal Replacement Therapy). There are two main types:

  • Hemodialysis (HD): Blood is pumped out of your body with the help of an artificial kidney (dialyzer) machine. It is then filtered and returned. This is usually done 3 times a week at a dialysis center or at home.

  • Peritoneal Dialysis (PD): A fluid is put into your abdominal cavity to pull waste products. This is done daily, usually at your home, overnight while you are sleeping with the help of a bedside machine.

Kidney Transplant: This is the most effective treatment. A healthy kidney from a deceased or living donor is surgically placed into the recipient. A successful transplant allows the patient to live without dialysis, offering a significant improvement in quality of life.

Prevent Kidney Failure

Prevention is always better than a cure. 

Since most cases of kidney failure are lifestyle-driven, a proactive approach can safeguard your kidney health.

  • Manage Your Numbers

Keep your blood pressure and blood sugar levels strictly within the target range. Regular monitoring is needed.

  • Hydration and Diet

Drink an adequate amount of water. Eat a balanced diet, focus on fresh foods, and limit processed foods that are high in salt and sugar. As the CKD stage advances, high potassium containing food items should be restricted.

  • NSAID Caution

NSAID pain killer medications can cause irreversible damage to the kidney and lead to end stage renal disease.

  • Quit Smoking

Smoking reduces your blood flow to the kidneys and worsens any existing damage.

  • Get Screened

If you have diabetes, high blood pressure, or a family history of kidney disease, get tests done regularly. 

Protect your Kidney Health 

Living with Kidney disease can be quite draining and stressful. During this time, it matters the care you choose for yourself.

Choosing the right hospital and care team for you will make sure you have a better journey and the best treatment. NU Hospitals, Bangalore, is a leader in kidney and urinary care. 

From early diagnosis and staging to dialysis and transplantation, you will get world-class expertise.

Take action today and protect your kidneys. 

Frequently Asked Questions On Kidney Failure:

1. What are the first signs of kidney failure?

The first signs of kidney failure are fatigue, swelling, breathlessness, loss of appetite, and reduced urine.

2. How long can a person live with kidney failure?

Life expectancy with kidney failure will vary from person to person on the basis of several factors such as age, overall health, and the type of treatment chosen.

3. What happens when your kidneys fail?

When your kidneys fail, waste products build up, swelling increases due to fluid retention, and it may lead to life threatening complications if not intervened early.

4. Can I reverse kidney damage?

Kidney damage can be reversed only in the early stages. Late stages are usually not reversible.

Dr. Ramprasad Ramalingam

Medically Reviewed By:

Dr. Ramprasad Ramalingam

Sr. Consultant Nephrologist & Transplant Physician

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