PSA Test (Prostate-Specific Antigen Test): Purpose & Results

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PSA Test (Prostate-Specific Antigen Test): Purpose & Results

How does prostate health affect men? What does a PSA test suggest? Should every man get a PSA screening done?

Let's find answers to all these questions in this blog.

Here are the key takeaways from today’s article:

  1. A PSA test is used for the early detection of prostate cancer. It is a blood test.

  2. The normal PSA levels change with age; what is normal at 45 may not be at the age of 65 

  3. High PSA levels could indicate benign enlargement, infection and malignant (cancerous) conditions of the prostate. 

  4. Men over the age of 45 with a family history should undergo PSA screening and digital rectal examinations by urologists.

  5. Early intervention and accurate diagnosis at NU Hospitals help with better outcomes.

What Is a PSA Test, and Why Does It Matter?

A PSA test helps you detect prostate infections, enlargement and cancer.

Prostate specific antigen is a protein produced by your prostate gland. The PSA test measures the amount of this protein.

PSA levels are higher when your prostate has inflammation, benign enlargement or has cancer growth.

Prostate is an important part of your urinary and reproductive system. 

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What Is a Normal PSA Level by Age?

Wondering what normal PSA levels are? Here are a few normal levels of PSA by age:

Age-adjusted normal PSA level

Age group

Normal range (ng/mL)

Borderline/high-risk range

40-49

0-2.5

2.6-4.0+

50-59

0-3.5

3.6-5.0+

60-69

0-4.5

4.6-6.0+

70+

0-6.5

6.6-8.0+

 As you age, the prostate gland tends to grow. The prostate releases more protein at an older age, even without cancer.

How Do You Prepare for PSA Screening?

A little preparation helps before PSA (Prostate Specific Antigen) screening.

  • Avoid cycling, heavy exercise and ejaculation for 24-48 hours before the test (if not, there are chances to find elevated levels)

  • Communicate everything with your urologist: your medication history, etc.

  • After the test, revisit your doctor to understand your situation

  • Follow routine tests as advised by your doctor

  • Ensure you take all medications and future steps as discussed

PSA Screening: What the Studies Say

Did you know?

With regular PSA screening, prostate cancer deaths were reduced by 13% – European study.

Another recent study found PSA screening reduced prostate cancer-specific mortality by 20-31% in selected groups.

Even though PSA tests are helpful, you should not do them all by yourself. It should be a shared decision between you and your doctor. Our experts will suggest what fits best for you.

What Causes Your PSA to Be High?

Are your PSA levels high? Does it mean something life-threatening? No, it could be anything.

The major causes of high PSA are:

  • Benign Prostatic Hyperplasia (BPH)

A benign (non-cancerous) enlargement of the prostate gland arising from age

  • Prostatitis

An infection or inflammation of the prostate is called prostatitis

  • Urinary tract infection

Can raise PSA temporarily

  • Recent surgery

Can raise PSA temporarily

  • Recent ejaculation or high-intense physical activity

It can also increase the levels temporarily

Comparing PSA Test with Digital Rectal Exam (DRE)

What is DRE? How is it different from PSA? Should you get both? Let’s find out!

Test

How it works

Detection

PSA test

A blood test to measure prostate-specific antigen levels

Chemical changes in the prostate gland

Digital Rectal Exam (DRE)

A physical exam to check the prostate through the rectum

To check the size, shape, and texture changes

 Our experts may advise both tests. A combined test can give a clear picture of the exact issue.

What If My PSA Is Elevated? What Next?

It is your time to be alert if your PSA levels are high. Here is what you should do next:

  • Repeat the test in a couple of months

This rules out any temporary spikes

  • Get a Total PSA ratio checked

When free/total PSA levels are lower, the higher the cancer risk

  • Your doctor might advise:

    • Prostate MRI (mp-MRI)

    • Transrectal Ultrasound (TRUS)

    • Biopsy of prostate (Transrectal or trans perineal)

  • Get the benefit of getting treated early with early detection.

We are here with you at all the steps of your journey: diagnosis, treatment and recovery.

PSA Test & Prostate Health: What Can You Do to Stay Ahead?

How can you maintain prostate health? Here are some tips from our experts:

  • Follow a healthy diet.

A diet rich with vegetables, lean protein, less red meat and salt

  • Exercise

Stay active with at least 30 minutes of exercise regularly

  • Quit smoking and alcohol consumption

Can reduce your risk of prostate issues

  • Maintain a healthy weight.

Does not stress your body

  • Monitor your blood pressure

High BP strains your body 

  • Routine PSA/DRE tests

Attend all your scheduled tests promptly

Frequently Asked Questions About PSA Test:

1. What is a normal PSA level by age?

At different ages, men have different normal PSA levels

<2.5 ng/ml - Men who are aged 40-49

<4.5 ng/mL - For men aged between 60 and 69

2. How do you prepare for a PSA test?

A few simple hacks, like not doing any strenuous activity, ejaculation, or workouts before the test, can help you get an accurate diagnosis.

3. Can PSA levels indicate prostate cancer?

Yes, PSA levels can indicate cancer, but high levels do not always mean cancer, as there are other causes too.

4. What causes high PSA levels?

Prostate enlargement, infection, inflammation, ejaculation, cycling, heavy workouts, and cancer can cause high PSA levels.

5. When should men get a PSA test?

Men above the age of 50 should get an annual PSA test done. If you are under the risk category, you should start as early as 45 years old.

Why Choose NU Hospitals for Your PSA Test & Prostate Health in Bangalore?

Choosing the best hospital guarantees better results. You deserve the best care from experts in Bangalore.

You get access to:

  • Expert urologists

Our vast team of urology experts have decades of experience and global expertise treating prostate problems.

  • Modern facilities

We are equipped with advanced state-of-the-art diagnosis techniques and tools, and provide accurate results in less time.

  • Tailored screenings

Our doctors will understand your situation and suggest what's best for you. You are unique, and so should be your screenings.

  • Patient-friendly environment

At NU Hospitals, the patient is the centre of care. We make sure all screenings, treatment and support are provided for your benefit.

  • World-class care

You can experience care that meets global standards but with less cost at the heart of Bangalore

Book Your PSA Screening at NU Hospitals Bangalore Today

Dear Men, are you also worried about your prostate health? Visit your nearest NU Hospitals today and consult our expert urologists!

Reference Links:

https://www.ncbi.nlm.nih.gov/books/NBK557495

https://pubmed.ncbi.nlm.nih.gov/41160819

https://www.mdpi.com/2227-9032/13/12/1381

https://journals.lww.com/indianjurol/fulltext/2023/39040/determining_age_specific_prostate_specific_antigen.10.aspx

Dr. Kumar Prabhu

Medically Reviewed By:

Dr. Kumar Prabhu

Sr. Consultant Urologist – Head of Department of Urology, NU Hospitals

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